Advancing Medical Reasoning with Reinforcement Learning from Verifiable Rewards (RLVR): Insights from MED-RLVR

Reinforcement Learning from Verifiable Rewards (RLVR) has recently emerged as a promising method for enhancing reasoning abilities in language models without direct supervision. This approach has shown notable success in mathematics and coding, where reasoning naturally aligns with structured problem-solving. While studies have demonstrated that RLVR alone can lead to self-evolved reasoning, research has largely been limited to these technical fields. Efforts to extend RLVR have explored synthetic datasets, such as those involving sequential tasks and object counting, indicating potential but also highlighting the challenges of adapting this method to different domains.

Expanding RLVR to broader areas remains an open challenge, particularly in tasks like multiple-choice question answering (MCQA), which provides structured, verifiable labels across diverse subjects, including medicine. However, unlike math and coding, which involve complex reasoning with an open-ended answer space, MCQA tasks typically have predefined answer choices, making it uncertain whether RLVR’s benefits translate effectively. This limitation is especially relevant in medical reasoning tasks, where models must navigate intricate clinical knowledge to produce accurate responses, an area that has proven difficult for existing AI systems.

Researchers from Microsoft Research investigate whether medical reasoning can emerge through RLVR. They introduce MED-RLVR, leveraging medical MCQA data to assess RLVR’s effectiveness in the medical domain. Their findings show that RLVR extends beyond math and coding, achieving performance comparable to supervised fine-tuning (SFT) in in-distribution tasks while significantly improving out-of-distribution generalization by eight percentage points. Analyzing training dynamics, they observe that reasoning capabilities emerge in a 3B-parameter base model without explicit supervision, highlighting RLVR’s potential for advancing reasoning in knowledge-intensive fields like medicine.

RL optimizes decision-making by training an agent to maximize rewards through interactions with an environment. It has been effectively applied to language models to align outputs with human preferences and, more recently, to elicit reasoning without explicit supervision. This study employs Proximal Policy Optimization (PPO) to train a policy model, incorporating a clipped objective function to stabilize training. Using a rule-based reward function, MED-RLVR assigns rewards based on output correctness and format validity. Without additional supervision, the model demonstrates emergent medical reasoning, similar to mathematical reasoning in prior RLVR studies, highlighting RLVR’s potential beyond structured domains.

The MedQA-USMLE dataset, which includes multi-choice medical exam questions, is used to train MED-RLVR. Unlike the standard four-option version, this dataset presents a greater challenge by offering more answer choices. Training is based on the Qwen2.5-3B model using OpenRLHF for reinforcement learning. Compared to SFT, MED-RLVR demonstrates superior generalization, particularly on the MMLU-Pro-Health dataset. Analysis reveals six stages of reasoning evolution: format failures, verbose outputs, reward hacking, and reintegrated reasoning. Unlike math or coding tasks, no self-validation behaviors (“aha-moments”) were observed, suggesting potential improvements through penalizing short reasoning chains or fine-tuning with longer CoTs.

In conclusion, the study focuses on MCQA in medicine, providing a controlled setting for evaluation. However, MCQA does not fully capture the complexity of real-world tasks like open-text answering, report generation, or medical dialogues. Additionally, the unimodal approach limits the model’s ability to integrate multimodal data, which is crucial for diagnostic applications. Future work should address these limitations. MED-RLVR, based on reinforcement learning with verifiable rewards, matches SFT on in-distribution tasks and improves out-of-distribution generalization. While medical reasoning emerges without explicit supervision, challenges like reward hacking persist, highlighting the need for further exploration of complex reasoning and multimodal integration.

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Sana Hassan, a consulting intern at Marktechpost and dual-degree student at IIT Madras, is passionate about applying technology and AI to address real-world challenges. With a keen interest in solving practical problems, he brings a fresh perspective to the intersection of AI and real-life solutions.